Cuadernos de Medicina Forense

40 PLIEGUE DEL LÓBULO DE LA OREJA EN ENFERMEDAD CORONARIA Monzó Blasco A, et al. Cuad Med Forense. 2022; 25(1):31 - 41 CUADERNOS DE MEDICINA FORENSE AS O C I AC I Ó N D E M É D I C O S FO R E N S ES D E A N DA LU C Í A S O C I E DA D A N DA LU Z A D E M E D I C I N A L EG A L Y C I E N C I AS FO R E N S ES ( A M FA- SA M E LC I F ) 3. Prangenberg J, Doberentz E, Johann L, Madea B. The prognostic value of the Frank sign. Forensic Sci Med Pathol.2022;18:149–155 4. Ishii T, Asuwa N, Masuda S, Ishikawa Y, Shimada K, Takemoto S. Earlobe Crease and Atherosclero- sis: An Autopsy Study. J Am Geriatr Soc. agosto de 1990;38(8):871-6. 5. Petrakis NL. Type A Behavior and the Death of Emperor Hadrian. West J Med.1980;132(1):87-91 6. Stoyanov GS, Dzhenkov D, Petkova L, Sapun- dzhiev N, Georgiev S. The Histological Basis of Frank’s Sign. Head Neck Pathol.2021;15(2):402-7. 7. Shoenfeld Y, Mor R, Weinberger A, Avidor I, Pinkhas J. Diagonal Ear Lobe Crease and Coro- nary Risk Factors. J Am Geriatr Soc.1980;28(4):184- 7. 8. Frank ST. Aural sign of coronary-artery disease. N Engl J Med.1973;289(6):327-8. 9. Wang Y, Mao LH, Jia EZ, Li ZY, Ding XQ, Ge PC, et al. Relationship between diagonal earlobe creases and coronary artery di- sease as determined via angiography. BMJ Open.2016;6(2):e008558. 10. Evrengül H, Dursunoğlu D, Kaftan A, Zoghi M, Tanrıverdi H, Zungur M, et al. Bilateral Dia- gonal Earlobe Crease and Coronary Artery Di- sease: A Significant Association. Dermatology. 2004;209(4):271-5. 11. Ramos PM, Gumieiro JH, Miot HA. Association be- tween ear creases and peripheral arterial disea- se. Clinics. 2010;65(12):1325-7. 12. Wu X li, Yang D you, Zhao Y sheng, Chai W hui, Jin M lei. Diagonal earlobe crease and coronary artery disease in a Chinese population. BMC Car- diovasc Disord. 2014;14(1):43. 13. Nazzal S, Hijazi B, Khalila L, Blum A. Diagonal Ear- lobe Crease (Frank’s Sign): A Predictor of Cere- bral Vascular Events. Am J Med.2017;130(11):1324. e1-1324.e5. 14. Pacei F, Bersano A, Brigo F, Reggiani S, Nardo- ne R. Diagonal earlobe crease (Frank’s sign) and increased risk of cerebrovascular diseases: re- view of the literature and implications for clinical practice. Neurol Sci.2020;41(2):257-62. 15. Cumberland, Gary D. M.D.; Riddick, LeRoy; Vinson, Richard. Earlobe Creases and Co- ronary Atherosclerosis The View from Fo- rensic Pathology. Am J Forensic Med Pa- thol.1987;8(1):9-11. 16. Ki r k h a m N, Murrells T, Melcher DH, Morri- son EA. Diagonal earlobe creases and fatal cardiovascular d i s e a s e : a n e c r o p s y s t u d y. He a r t . 1 9 8 9 ; 6 1 ( 4 ) : 3 6 1 - 4 . 1 7 . E dston E. The Earlobe Crease, Coronary Artery Disease, and Sudden Cardiac Death: An Au- topsy Study of 520 Individuals. Am J Forensic Med Pathol.2006;27(2):129-3 3. 18. Mallinson TE, Brooke D. Limited Diagnostic Potential of Diagonal Earlobe Crease. Ann Emerg Med.2017;70(4):602-3. 19. Davis TME, Balme M, Jackson D, Stuccio G, Bruce DG. The diagonal ear lobe crease (Frank’s sign) is not associated with coronary artery disease or retinopathy in type 2 diabe- tes: the Fremantle Diabetes Study. Aust N Z J Med.2000;30(5):573-7. 20. Kenny DJ, Gilligan D. Ear Lobe Crease and Coronary Artery Disease in Patients Under- going Coronary Arteriography. Cardiology. 1989;76(4):293-8. 21. Gral T, Thornburg M. Earlobe Creases in a Cohort of Elderly Veterans. J Am Geriatr Soc.1983;31(3):134-6. 22. Basso C, Aguilera B, Banner J, Cohle S, d’Ama- ti G, de Gouveia RH, et al. Guidelines for au- topsy investigation of sudden cardiac dea- th: 2017 update from the Association for European Cardiovascular Pathology. Virchows Arch.2017;471(6):691-705. 23. Cañadas EV. Gisbert Calabuig. Medicina Legal y Toxicología. 7ª Edición. Elsevier Health Scien- ces; 2018. 1486 p. 24. Rodríguez-López C, Garlito-Díaz H, Madro- ñero-Mariscal R, Sánchez-Cervilla PJ, Gracia- ni A, López-Sendón JL, et al. Earlobe Crease Shapes and Cardiovascular Events. Am J Car- diol.2015;116(2):286-93. 25. Ascariz LF. Signo de Frank y riesgo cardio- vascular. Un estudio epidemiológico [Inter-