Cuadernos de Medicina Forense

PROLAPSO MITRAL Y MUERTE SÚBITA CARDIACA Garamendi PM, et al. Cuad Med Forense. 2025; 28(1):9-17 16 CUADERNOS DE MEDICINA FORENSE A S O C I AC I Ó N D E M É D I C O S FO R E N S E S D E A N DA LU C Í A S O C I E DA D A N DA LU Z A D E M E D I C I N A L EG A L Y C I E N C I A S FO R E N S E S ( A M FA - SA M E LC I F ) AGRADECIMIENTOS A los doctores Ana Manovel y Javier Mendoza por su colaboración en el estudio de este caso clínico. CONFLICTO DE INTERESES Los autores/as de este artículo declaran no te- ner ningún tipo de conflicto de intereses res- pecto a lo expuesto en el presente trabajo. FUENTES DE FINANCIACIÓN Ninguna. BIBLIOGRAFÍA 1. Guidelines for autopsy investigation of sudden cardiac death: 2017 update from the Association for European Cardiovascular Pathology 2. Richards S, Aziz N, Bale S et al. Standards and guidelines for the interpretation of sequen- ce variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecu- lar Pathology. Genet Med.2015;17(5):405-24. doi: 10.1038/gim.2015.30. Epub 2015 Mar 5. Disponi- ble en: https://pmc.ncbi.nlm.nih.gov/articles/ PMC4544753/. 3. Ellard S, Baple EL, Berry I et al. ACGS best practice guidelines for variant classification 2020: association for clinical genetics science (ACGS), 2020. Available:  https://www.acgs.uk. com/qua l i t y/be s t - p r ac t i ce - gu i de l i ne s /#Va - riantGuidelines 4. Sheppard M. Practical cardiovascular pathology. 3Rd edition. CRC Press. Boca Ratón, FL. 2022. 5. Kitkungvan D, Nabi F, Kim RJ et al. Myocardial Fi - brosis in Patients With Primary Mitral Regurgita- tion With and Without Prolapse. J Am Coll Cardiol 2018;72:823–34. 6. Vriz O, Landi I, Eltayeb A et al. Mitral Val- ve Prolapse and Sudden Cardiac Death in Athletes at High Risk. Curr Cardiol Rev. 2023;19(3):e201222212066 7. Battaglia V, Santangelo G, Bursi F et al, Arrhyth- mogenic Mitral Valve Prolapse and Sudden Car- diac Death: An Update and Current Perspectives. Curr Probl Cardiol.2013;48(7):101724. 8. Sabbag A, Essayagh B, Ramírez-Barrera JD, Bas- so C et al. EHRA expert consensus statement on arrhythmic mitral valve prolapse and mitral an- nular disjunction complex in collaboration with the ESC Council on valvular heart disease and the European Association of Cardiovascular Ima- ging endorsed, by the Heart Rhythm Society, by the Asia Pacific Heart Rhythm Society, and by the Latin American Heart Rhythm Society. Europa- ce.2022;24:1981-2003 9. Spartalis M, Tzatzaki E, Spartalis E et al. Mitral valve prolapse: an underestimated cause of sud- den cardiac death—a current review of the litera- ture. J Thorac Dis 2017;9(12):5390-5398 10. Sriram CS, Syed FF, Ferguson E et al. Malig- nant Bileaflet Mitral Valve Prolapse Syndro- me in Patients With Otherwise Idiopathic Out-of-Hospital Cardiac Arrest. J Am Coll Car- diol 2013;62:222–30 11. Korovesis TG, Koutrlou-Sotiropoulou P, Ka- tritsis DG. Arrhytmogenic mitral valve prolap- se. Arrhythmia & Electrophysiology Review 2022;11:e16. 12. Molina DK. Handbook of forensic toxicolo - gy for medical examiners. Boca Raton FL CRC Press.2010. 359p 13. Karch SB, Drummer OH. Karch´s Pathology of drug abuse. Fifth Edition. Boca Raton:CRCPRess.2016. 906p 14. Drummer OH, Gerostamoulos D, Woodford NW. Cannabis as a cause of death: a review. Forensic Sci Int.2019;298:298-306. 15. Lee A, Jin C, Fan Y, et al. Functional impli- cation of mitral annular disjunction in mitral valve prolapse. A Quantitative Dynamic 3D Echocardiographic Study. JACC Cardiovasc Imaging. 2017;10(12):1424-1433. doi: 10.1016/j. jcmg.2016.11.022.